4DG6

Crystal structure of domains 1 and 2 of LRP6

Summary for 4DG6

• Entry DOI: 10.2210/pdb4dg6/pdb
• Descriptor: Low-density lipoprotein receptor-related protein 6, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATE ION, ... (4 entities in total)
• Functional Keywords: 6-bladed beta propeller, sclerostin receptor, egf, wnt, mesd, signaling protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 71071.71

Authors

Ceska, T.A.,Doyle, C.,Slocombe, P. (deposition date: 2012-01-25, release date: 2012-06-13, Last modification date: 2020-07-29)

• Primary citation: Holdsworth, G.,Slocombe, P.,Doyle, C.,Sweeney, B.,Veverka, V.,Le Rich, K.,Franklin, R.J.,Brookings, D.,Turner, J.,Kennedy, J.,Garlish, R.,Shi, J.,Newnham, L.,McMillan, D.,Muzylak, M.,Carr, M.,Henry, A.J.,Ceska, T.,Robinson, M.K.; Characterization of the interaction of sclerostin with the LRP family of Wnt co-receptors; To be Published,

Experimental method

X-RAY DIFFRACTION (2.9 Å)