4DC0
Crystal Structure of F189W Actinorhodin Polyketide Ketoreductase with NADPH
Summary for 4DC0
Entry DOI | 10.2210/pdb4dc0/pdb |
Related | 4DBZ 4DC1 |
Descriptor | Ketoacyl reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total) |
Functional Keywords | rossmann fold, short-chain dehydrogenase/reductase, ketoreductase, oxidoreductase |
Biological source | Streptomyces coelicolor |
Total number of polymer chains | 2 |
Total formula weight | 60497.63 |
Authors | Javidpour, P.,Tsai, S.-C. (deposition date: 2012-01-16, release date: 2013-01-16, Last modification date: 2024-02-28) |
Primary citation | Javidpour, P.,Bruegger, J.,Srithahan, S.,Korman, T.P.,Crump, M.P.,Crosby, J.,Burkart, M.D.,Tsai, S.C. The Determinants of Activity and Specificity in Actinorhodin Type II Polyketide Ketoreductase. Chem.Biol., 20:1225-1234, 2013 Cited by PubMed: 24035284DOI: 10.1016/j.chembiol.2013.07.016 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.813 Å) |
Structure validation
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