4DBX

Crystal structure of aminoglycoside phosphotransferase APH(2")-ID/APH(2")-IVA

Replaces:  3R7ZReplaces:  3LZH

Summary for 4DBX

• Entry DOI: 10.2210/pdb4dbx/pdb
• Related: 4DE4 4DFB 4DFU
• Descriptor: APH(2")-ID (2 entities in total)
• Functional Keywords: structural genomics, mcsg, midwest center for structural genomics, eukaryotic protein kinase-like fold, aminoglycoside phosphotransferase, kinase, transferase, aminoglycosides, intracellular, psi-biology
• Biological source: Enterococcus casseliflavus
• Total number of polymer chains: 1
• Total formula weight: 38279.04

Authors

Stogios, P.J.,Minasov, G.,Tan, K.,Nocek, B.,Singer, A.U.,Evdokimova, E.,Egorova, E.,Di Leo, R.,Li, H.,Shakya, T.,Wright, G.D.,Savchenko, A.,Anderson, W.F.,Midwest Center for Structural Genomics (MCSG) (deposition date: 2012-01-16, release date: 2012-02-01, Last modification date: 2012-04-25)

• Primary citation: Shakya, T.,Stogios, P.J.,Waglechner, N.,Evdokimova, E.,Ejim, L.,Blanchard, J.E.,McArthur, A.G.,Savchenko, A.,Wright, G.D.; A small molecule discrimination map of the antibiotic resistance kinome.; Chem.Biol., 18:1591-1601, 2011; PubMed: 22195561; DOI: 10.1016/j.chembiol.2011.10.018

Experimental method

X-RAY DIFFRACTION (2.004 Å)