4CRU
Complex of human CNOT9 and CNOT1 including one tryptophan
Summary for 4CRU
Entry DOI | 10.2210/pdb4cru/pdb |
Related | 2FV2 4CRV |
Descriptor | CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CELL DIFFERENTIATION PROTEIN RCD1 HOMOLOG, GLYCEROL, ... (4 entities in total) |
Functional Keywords | gene regulation, tnrc6 binding, mirisc, mrna silencing, mrna deadenylation, argonaute, transcription |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Cytoplasm, P-body: A5YKK6 Nucleus (By similarity): Q92600 |
Total number of polymer chains | 2 |
Total formula weight | 60430.98 |
Authors | Chen, Y.,Boland, A.,Izaurralde, E.,Weichenrieder, O. (deposition date: 2014-03-01, release date: 2014-05-07, Last modification date: 2023-12-20) |
Primary citation | Chen, Y.,Boland, A.,Kuzuoglu-Ozturk, D.,Bawankar, P.,Loh, B.,Chang, C.T.,Weichenrieder, O.,Izaurralde, E. A Ddx6-Cnot1 Complex and W-Binding Pockets in Cnot9 Reveal Direct Links between Mirna Target Recognition and Silencing Mol.Cell, 54:737-, 2014 Cited by PubMed: 24768540DOI: 10.1016/J.MOLCEL.2014.03.034 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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