4CMQ
Crystal structure of Mn-bound S.pyogenes Cas9
Summary for 4CMQ
Entry DOI | 10.2210/pdb4cmq/pdb |
Related | 4CMP |
Descriptor | CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MANGANESE (II) ION, SULFATE ION (3 entities in total) |
Functional Keywords | hydrolase, dnase, endonuclease, rna-guided, immunity, crrna, genome editing |
Biological source | STREPTOCOCCUS PYOGENES |
Total number of polymer chains | 2 |
Total formula weight | 319262.79 |
Authors | Jinek, M.,Jiang, F.,Taylor, D.W.,Sternberg, S.H.,Kaya, E.,Ma, E.,Anders, C.,Hauer, M.,Zhou, K.,Lin, S.,Kaplan, M.,Iavarone, A.T.,Charpentier, E.,Nogales, E.,Doudna, J.A. (deposition date: 2014-01-17, release date: 2014-02-12, Last modification date: 2023-12-20) |
Primary citation | Jinek, M.,Jiang, F.,Taylor, D.W.,Sternberg, S.H.,Kaya, E.,Ma, E.,Anders, C.,Hauer, M.,Zhou, K.,Lin, S.,Kaplan, M.,Iavarone, A.T.,Charpentier, E.,Nogales, E.,Doudna, J.A. Structures of Cas9 Endonucleases Reveal RNA- Mediated Conformational Activation Science, 343:47997-, 2014 Cited by PubMed: 24505130DOI: 10.1126/SCIENCE.1247997 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.09 Å) |
Structure validation
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