4CL0

Structure of the Mycobacterium tuberculosis Type II Dehydroquinase inhibited by a 3-dehydroquinic acid derivative

Summary for 4CL0

• Entry DOI: 10.2210/pdb4cl0/pdb
• Related: 4CKW 4CKX 4CKY 4CKZ
• Descriptor: 3-DEHYDROQUINATE DEHYDRATASE, (2R)-2-METHYL-3-DEHYDROQUINIC ACID (3 entities in total)
• Functional Keywords: bacterial proteins, type 2 dehydroquinase, lyase, inhibitor, protein binding, shikimis acid pathway, substrate specificity
• Biological source: MYCOBACTERIUM TUBERCULOSIS
• Total number of polymer chains: 1
• Total formula weight: 15880.91

Authors

Otero, J.M.,Llamas-Saiz, A.L.,Maneiro, M.,Peon, A.,Sedes, A.,Lamb, H.,Hawkins, A.R.,Gonzalez-Bello, C.,van Raaij, M.J. (deposition date: 2014-01-10, release date: 2015-03-25, Last modification date: 2023-12-20)

• Primary citation: Maneiro, M.,Otero, J.M.,Peon, A.,Sedes, A.,Llamas-Saiz, A.L.,Lamb, H.,Hawkins, A.R.,van Raaij, M.J.,Gonzalez-Bello, C.; Investigation of the Dehydratation Mechanism Catalyzed by the Type II Dehydroquinase; To be Published,

Experimental method

X-RAY DIFFRACTION (3.1 Å)