4CBL

Pestivirus NS3 helicase

Summary for 4CBL

Entry DOI	10.2210/pdb4cbl/pdb
Related	4CBG 4CBH 4CBI 4CBM
Descriptor	SERINE PROTEASE NS3 (1 entity in total)
Functional Keywords	hydrolase, sf2 helicases, pestivirus, flaviviridae ns3, saxs
Biological source	CLASSICAL SWINE FEVER VIRUS
Cellular location	E(rns) glycoprotein: Host membrane; Peripheral membrane protein. Envelope glycoprotein E2: Host cell surface . Cysteine protease NS2: Host membrane ; Multi-pass membrane protein : P19712
Total number of polymer chains	4
Total formula weight	228880.76
Authors	Tortorici, M.A.,Duquerroy, S.,Kwok, J.,Vonrhein, C.,Perez, J.,Lamp, B.,Bricogne, G.,Rumenapf, T.,Vachette, P.,Rey, F.A. (deposition date: 2013-10-14, release date: 2015-01-21, Last modification date: 2023-12-20)
Primary citation	Tortorici, M.A.,Duquerroy, S.,Kwok, J.,Vonrhein, C.,Perez, J.,Lamp, B.,Bricogne, G.,Rumenapf, T.,Vachette, P.,Rey, F.A. X-Ray Structure of the Pestivirus Ns3 Helicase and its Conformation in Solution. J.Virol., 89:4356-, 2015 Cited by PubMed: 25653438 DOI: 10.1128/JVI.03165-14 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.05 Å)

Structure validation