4C5A

The X-ray crystal structures of D-alanyl-D-alanine ligase in complex ADP and D-cycloserine phosphate

Summary for 4C5A

Entry DOI	10.2210/pdb4c5a/pdb
Related	4C5B 4C5C
Descriptor	D-ALANINE--D-ALANINE LIGASE, PEPTIDE, ADENOSINE-5'-DIPHOSPHATE, ... (7 entities in total)
Functional Keywords	ligase, ddlb, antibiotic
Biological source	ESCHERICHIA COLI K-12 More
Total number of polymer chains	3
Total formula weight	74122.52
Authors	Batson, S.,Majce, V.,Lloyd, A.J.,Rea, D.,Fishwick, C.W.G.,Simmons, K.J.,Fulop, V.,Roper, D.I. (deposition date: 2013-09-10, release date: 2015-01-21, Last modification date: 2023-12-20)
Primary citation	Batson, S.,de Chiara, C.,Majce, V.,Lloyd, A.J.,Gobec, S.,Rea, D.,Fulop, V.,Thoroughgood, C.W.,Simmons, K.J.,Dowson, C.G.,Fishwick, C.W.G.,de Carvalho, L.P.S.,Roper, D.I. Inhibition of D-Ala:D-Ala ligase through a phosphorylated form of the antibiotic D-cycloserine. Nat Commun, 8:1939-1939, 2017 Cited by PubMed: 29208891 DOI: 10.1038/s41467-017-02118-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.65 Å)

Structure validation