4C3Q

Neutron structure of a perdeuterated Toho-1 R274N R276N double mutant Beta-lactamase in complex with a fully deuterated boronic acid (BZB) at 100K

Summary for 4C3Q

Entry DOI	10.2210/pdb4c3q/pdb
Descriptor	BETA-LACTAMASE TOHO-1, BENZO[B]THIOPHENE-2-BORONIC ACID (3 entities in total)
Functional Keywords	hydrolase, toho-1, perdeuterated neutron structure, extended-spectrum beta lactamases, ctx- m-type esbls, cryogenic neutron
Biological source	ESCHERICHIA COLI
Total number of polymer chains	1
Total formula weight	28282.73
Authors	Coates, L.,Tomanicek, S.J.,Schrader, T.,Weiss, K.L.,Ng, J.D.,Ostermann, A. (deposition date: 2013-08-26, release date: 2014-07-09, Last modification date: 2017-03-22)
Primary citation	Coates, L.,Tomanicek, S.J.,Schrader, T.,Weiss, K.L.,Ng, J.D.,Ostermann, A. Cryogenic Neutron Protein Crystallography: Routine Methods and Potential Benefits J.Appl.Crystallogr., 47:-, 2014 Cited by DOI: 10.1107/S1600576714010772 PDB entries with the same primary citation
Experimental method	NEUTRON DIFFRACTION (2.2 Å)

Structure validation