4BXL
Structure of alpha-synuclein in complex with an engineered binding protein
Summary for 4BXL
Entry DOI | 10.2210/pdb4bxl/pdb |
Descriptor | AS69, ALPHA SYNUCLEIN (2 entities in total) |
Functional Keywords | fibril, amyloid, parkinson's disease, protein aggregation, protein engineering, protein misfolding, scaffold proteins |
Biological source | SYNTHETIC CONSTRUCT More |
Cellular location | Cytoplasm: P37840 |
Total number of polymer chains | 3 |
Total formula weight | 12380.70 |
Authors | Mirecka, E.A.,Shaykhalishahi, H.,Lecher, J.,Stoldt, M.,Hoyer, W. (deposition date: 2013-07-12, release date: 2014-05-21) |
Primary citation | Mirecka, E.A.,Shaykhalishahi, H.,Gauhar, A.,Akgul, S.,Lecher, J.,Willbold, D.,Stoldt, M.,Hoyer, W. Sequestration of a Beta-Hairpin for Control of Alpha-Synuclein Aggregation. Angew.Chem.Int.Ed.Engl., 53:4227-, 2014 Cited by PubMed: 24623599DOI: 10.1002/ANIE.201309001 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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