4B8E

PRY-SPRY domain of Trim25

Summary for 4B8E

Entry DOI	10.2210/pdb4b8e/pdb
Descriptor	E3 UBIQUITIN/ISG15 LIGASE TRIM25, CHLORIDE ION, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	ligase
Biological source	MUS MUSCULUS (HOUSE MOUSE)
Cellular location	Cytoplasm (By similarity): Q61510
Total number of polymer chains	2
Total formula weight	45164.05
Authors	Kershaw, N.J.,D'Cruz, A.A.,Nicola, N.A.,Nicholson, S.E.,Babon, J.J. (deposition date: 2012-08-27, release date: 2013-09-04, Last modification date: 2023-12-20)
Primary citation	D'Cruz, A.A.,Kershaw, N.J.,Chiang, J.J.,Wang, M.K.,Nicola, N.A.,Babon, J.J.,Gack, M.U.,Nicholson, S.E. Crystal Structure of the Trim25 B30.2 (Pryspry) Domain: A Key Component of Antiviral Signaling. Biochem.J., 456:231-, 2013 Cited by PubMed: 24015671 DOI: 10.1042/BJ20121425 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.779 Å)

Structure validation