4B4V
Crystal structure of Acinetobacter baumannii N5, N10- methylenetetrahydrofolate dehydrogenase-cyclohydrolase (FolD) complexed with NADP cofactor and inhibitor LY354899
Summary for 4B4V
Entry DOI | 10.2210/pdb4b4v/pdb |
Related | 4B4U 4B4W |
Descriptor | BIFUNCTIONAL PROTEIN FOLD, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, GLYCEROL, ... (6 entities in total) |
Functional Keywords | oxidoreductase, inhibitor |
Biological source | ACINETOBACTER BAUMANNII ATCC 19606 |
Total number of polymer chains | 2 |
Total formula weight | 66941.31 |
Authors | Eadsforth, T.C.,Maluf, F.V.,Hunter, W.N. (deposition date: 2012-08-01, release date: 2012-08-22, Last modification date: 2023-12-20) |
Primary citation | Eadsforth, T.C.,Maluf, F.V.,Hunter, W.N. Acinetobacter Baumannii Fold Ligand Complexes; Potent Inhibitors of Folate Metabolism and a Re-Evaluation of the Ly374571 Structure. FEBS J., 279:4350-, 2012 Cited by PubMed: 23050773DOI: 10.1111/FEBS.12025 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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