4AZ1
Crystal structure of the Trypanosoma cruzi protein tyrosine phosphatase TcPTP1, a potential therapeutic target for Chagas' disease
Summary for 4AZ1
Entry DOI | 10.2210/pdb4az1/pdb |
Descriptor | TYROSINE SPECIFIC PROTEIN PHOSPHATASE, 1,2-ETHANEDIOL, FORMIC ACID, ... (4 entities in total) |
Functional Keywords | hydrolase, drug design |
Biological source | TRYPANOSOMA CRUZI |
Total number of polymer chains | 2 |
Total formula weight | 67963.60 |
Authors | Lountos, G.T.,Tropea, J.E.,Waugh, D.S. (deposition date: 2012-06-22, release date: 2012-11-21, Last modification date: 2023-12-20) |
Primary citation | Lountos, G.T.,Tropea, J.E.,Waugh, D.S. Structure of the Trypanosoma Cruzi Protein Tyrosine Phosphatase Tcptp1, a Potential Therapeutic Target for Chagas' Disease. Mol.Biochem.Parasitol., 187:1-, 2012 Cited by PubMed: 23137716DOI: 10.1016/J.MOLBIOPARA.2012.10.006 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.181 Å) |
Structure validation
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