4ATZ

Ad5 knob in complex with a designed ankyrin repeat protein

Summary for 4ATZ

• Entry DOI: 10.2210/pdb4atz/pdb
• Related: 1KNB
• Descriptor: Fiber protein, DESIGNED ANKYRIN REPEAT PROTEIN (3 entities in total)
• Functional Keywords: viral protein-de novo protein complex, darpin, protein design, viral protein/de novo protein
• Biological source: Human adenovirus C serotype 5 (HAdV-5); More
• Total number of polymer chains: 6
• Total formula weight: 115085.82

Authors

Mittl, P.R.E.,Hess, C.,Dreier, B. (deposition date: 2012-05-11, release date: 2013-02-27, Last modification date: 2023-12-20)

• Primary citation: Dreier, B.,Honegger, A.,Hess, C.,Nagy-Davidescu, G.,Mittl, P.R.,Grutter, M.G.,Belousova, N.,Mikheeva, G.,Krasnykh, V.,Pluckthun, A.; Development of a generic adenovirus delivery system based on structure-guided design of bispecific trimeric DARPin adapters.; Proc. Natl. Acad. Sci. U.S.A., 110:E869-E877, 2013; PubMed: 23431166; DOI: 10.1073/pnas.1213653110

Experimental method

X-RAY DIFFRACTION (1.95 Å)