4ANM

Complex of CK2 with a CDC7 inhibitor

Summary for 4ANM

Entry DOI	10.2210/pdb4anm/pdb
Related	1DAW 1DAY 1DS5 1F0Q 1J91 1JAM 1LP4 1LPU 1LR4 1M2P 1M2Q 1M2R 1OM1 1ZOE 1ZOG 1ZOH
Descriptor	CASEIN KINASE II SUBUNIT ALPHA, 8-BROMANYL-2-[[(3S)-3-OXIDANYLPYRROLIDIN-1-YL]METHYL]-3H-[1]BENZOFURO[3,2-D]PYRIMIDIN-4-ONE (3 entities in total)
Functional Keywords	transferase
Biological source	ZEA MAYS (MAIZE)
Total number of polymer chains	1
Total formula weight	39944.58
Authors	Stout, T.J. (deposition date: 2012-03-20, release date: 2012-05-23, Last modification date: 2024-05-01)
Primary citation	Koltun, E.S.,Tsuhako, A.L.,Brown, D.S.,Aay, N.,Arcalas, A.,Chan, V.,Du, H.,Engst, S.,Ferguson, K.,Franzini, M.,Galan, A.,Holst, C.R.,Huang, P.,Kane, B.,Kim, M.H.,Li, J.,Markby, D.,Mohan, M.,Noson, K.,Plonowski, A.,Richards, S.J.,Robertson, S.,Shaw, K.,Stott, G.,Stout, T.J.,Young, J.,Yu, P.,Zaharia, C.A.,Zhang, W.,Zhou, P.,Nuss, J.M.,Xu, W.,Kearney, P.C. Discovery of Xl413, a Potent and Selective Cdc7 Inhibitor. Bioorg.Med.Chem.Lett., 22:3727-, 2012 Cited by PubMed: 22560567 DOI: 10.1016/J.BMCL.2012.04.024 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation