4AK2

Structure of BT4661, a SusE-like surface located polysaccharide binding protein from the Bacteroides thetaiotaomicron heparin utilisation locus

Summary for 4AK2

• Entry DOI: 10.2210/pdb4ak2/pdb
• Related: 4AK1
• Descriptor: BT_4661, 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, SODIUM ION, ... (4 entities in total)
• Functional Keywords: heparin-binding protein, heparan sulphate
• Biological source: BACTEROIDES THETAIOTAOMICRON
• Total number of polymer chains: 1
• Total formula weight: 33802.10

Authors

Lowe, E.C.,Basle, A.,Czjzek, M.,Thomas, S.,Murray, H.,Firbank, S.J.,Bolam, D.N. (deposition date: 2012-02-21, release date: 2013-03-06, Last modification date: 2020-07-29)

• Primary citation: Cartmell, A.,Lowe, E.C.,Basle, A.,Firbank, S.J.,Ndeh, D.A.,Murray, H.,Terrapon, N.,Lombard, V.,Henrissat, B.,Turnbull, J.E.,Czjzek, M.,Gilbert, H.J.,Bolam, D.N.; How members of the human gut microbiota overcome the sulfation problem posed by glycosaminoglycans.; Proc. Natl. Acad. Sci. U.S.A., 114:7037-7042, 2017; PubMed: 28630303; DOI: 10.1073/pnas.1704367114

Experimental method

X-RAY DIFFRACTION (1.35 Å)