4AG3
Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with NADPH at 1.8A resolution
Summary for 4AG3
Entry DOI | 10.2210/pdb4ag3/pdb |
Related | 4AFN |
Descriptor | 3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PENTAETHYLENE GLYCOL, ... (4 entities in total) |
Functional Keywords | fatty acid biosynthesis, oxidoreductase, rossmann fold |
Biological source | PSEUDOMONAS AERUGINOSA |
Total number of polymer chains | 4 |
Total formula weight | 116814.33 |
Authors | Cukier, C.D.,Schnell, R.,Schneider, G.,Lindqvist, Y. (deposition date: 2012-01-24, release date: 2013-02-06, Last modification date: 2023-12-20) |
Primary citation | Cukier, C.D.,Hope, A.,Elamin, A.,Moynie, L.,Schnell, R.,Schach, S.,Kneuper, H.,Singh, M.,Naismith, J.,Lindqvist, Y.,Gray, D.,Schneider, G. Discovery of an Allosteric Inhibitor Binding Site in 3-Oxo-Acyl-Acp Reductase from Pseudomonas Aeruginosa Acs Chem.Biol., 8:2518-, 2013 Cited by PubMed: 24015914DOI: 10.1021/CB4005063 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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