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4A4B

Structure of modified phosphoTyr371-c-Cbl-UbcH5B-ZAP-70 complex

Summary for 4A4B
Entry DOI10.2210/pdb4a4b/pdb
Related1B47 1FBV 1M61 1U59 1UR6 1W4U 1YVH 2C4O 2CBL 2CLW 2ESK 2ESO 2ESP 2ESQ 2Y1M 2Y1N 4A49 4A4C
DescriptorE3 UBIQUITIN-PROTEIN LIGASE CBL, TYROSINE-PROTEIN KINASE ZAP-70, UBIQUITIN-CONJUGATING ENZYME E2 D2, ... (6 entities in total)
Functional Keywordsligase-transferase complex, ligase/transferase
Biological sourceHOMO SAPIENS (HUMAN)
More
Cellular locationCytoplasm: P22681 P43403
Total number of polymer chains3
Total formula weight63407.20
Authors
Dou, H.,Buetow, L.,Hock, A.,Sibbet, G.J.,Vousden, K.H.,Huang, D.T. (deposition date: 2011-10-08, release date: 2012-01-25, Last modification date: 2023-12-20)
Primary citationDou, H.,Buetow, L.,Hock, A.,Sibbet, G.J.,Vousden, K.H.,Huang, D.T.
Structural Basis for Autoinhibition and Phosphorylation-Dependent Activation of C-Cbl
Nat.Struct.Mol.Biol., 19:184-, 2012
Cited by
PubMed: 22266821
DOI: 10.1038/NSMB.2231
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.789 Å)
Structure validation

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