3ZMP
Src-derived peptide inhibitor complex of PTP1B
Summary for 3ZMP
Entry DOI | 10.2210/pdb3zmp/pdb |
Descriptor | TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC (3 entities in total) |
Functional Keywords | hydrolase-peptide complex, enzyme inhibitors, structure-activity relationship, transferase, hydrolase/peptide |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side : P18031 Cell membrane: P12931 |
Total number of polymer chains | 4 |
Total formula weight | 79471.99 |
Authors | Temmerman, K.,Pogenberg, V.,Meyer, C.,Koehn, M.,Wilmanns, M. (deposition date: 2013-02-12, release date: 2014-01-22, Last modification date: 2023-12-20) |
Primary citation | Meyer, C.,Hoeger, B.,Temmerman, K.,Tatarek-Nossol, M.,Pogenberg, V.,Bernhagen, J.,Wilmanns, M.,Kapurniotu, A.,Kohn, M. Development of Accessible Peptidic Tool Compounds to Study the Phosphatase Ptp1B in Intact Cells. Acs Chem.Biol., 9:769-, 2014 Cited by PubMed: 24387659DOI: 10.1021/CB400903U PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.619 Å) |
Structure validation
Download full validation report