3ZKR

X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with bromoform

Summary for 3ZKR

• Entry DOI: 10.2210/pdb3zkr/pdb
• Descriptor: CYS-LOOP LIGAND-GATED ION CHANNEL, TRIBROMOMETHANE (2 entities in total)
• Functional Keywords: transport protein, cys-loop receptor, gaba-a receptor, general anesthetics
• Biological source: ERWINIA CHRYSANTHEMI
• Cellular location: Cell inner membrane; Multi-pass membrane protein (Probable): P0C7B7
• Total number of polymer chains: 10
• Total formula weight: 359393.75

Authors

Spurny, R.,Billen, B.,Howard, R.J.,Brams, M.,Debaveye, S.,Price, K.L.,Weston, D.A.,Strelkov, S.V.,Tytgat, J.,Bertrand, S.,Bertrand, D.,Lummis, S.C.R.,Ulens, C. (deposition date: 2013-01-24, release date: 2013-02-06, Last modification date: 2014-09-17)

• Primary citation: Spurny, R.,Billen, B.,Howard, R.J.,Brams, M.,Debaveye, S.,Price, K.L.,Weston, D.A.,Strelkov, S.V.,Tytgat, J.,Bertrand, S.,Bertrand, D.,Lummis, S.C.R.,Ulens, C.; Multisite Binding of a General Anesthetic to the Prokaryotic Pentameric Erwinia Chrysanthemi Ligand-Gated Ion Channel (Elic).; J.Biol.Chem., 288:8355-, 2013; PubMed: 23364792; DOI: 10.1074/JBC.M112.424507

Experimental method

X-RAY DIFFRACTION (3.649 Å)