3WK8
Crystal structure of soluble epoxide hydrolase in complex with fragment inhibitor
Summary for 3WK8
| Entry DOI | 10.2210/pdb3wk8/pdb |
| Related | 3WK4 3WK5 3WK6 3WK7 3WK9 3WKA 3WKB 3WKC 3WKD 3WKE |
| Descriptor | Bifunctional epoxide hydrolase 2, MAGNESIUM ION, PHOSPHATE ION, ... (5 entities in total) |
| Functional Keywords | hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: P34913 |
| Total number of polymer chains | 1 |
| Total formula weight | 63851.99 |
| Authors | Amano, Y.,Yamaguchi, T.,Tanabe, E. (deposition date: 2013-10-17, release date: 2014-04-16, Last modification date: 2022-08-24) |
| Primary citation | Amano, Y.,Yamaguchi, T.,Tanabe, E. Structural insights into binding of inhibitors to soluble epoxide hydrolase gained by fragment screening and X-ray crystallography. Bioorg.Med.Chem., 22:2427-2434, 2014 Cited by PubMed: 24656800DOI: 10.1016/j.bmc.2014.03.001 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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