3W1S
Crystal structure of Saccharomyces cerevisiae Atg12-Atg5 conjugate bound to the N-terminal domain of Atg16
Summary for 3W1S
Entry DOI | 10.2210/pdb3w1s/pdb |
Descriptor | Autophagy protein 5, Autophagy protein 16, Ubiquitin-like protein ATG12, ... (4 entities in total) |
Functional Keywords | ubiquitin fold, e3-like, atg3 binding, isopeptide bond between atg12 gly186 and atg5 lys149, ligase |
Biological source | Saccharomyces cerevisiae S288c (Baker's yeast) More |
Cellular location | Cytoplasm: Q12380 Preautophagosomal structure membrane; Peripheral membrane protein: Q03818 P38316 |
Total number of polymer chains | 3 |
Total formula weight | 48754.49 |
Authors | Noda, N.N.,Fujioka, Y.,Hanada, T.,Ohsumi, Y.,Inagaki, F. (deposition date: 2012-11-20, release date: 2012-12-26, Last modification date: 2023-11-08) |
Primary citation | Noda, N.N.,Fujioka, Y.,Hanada, T.,Ohsumi, Y.,Inagaki, F. Structure of the Atg12-Atg5 conjugate reveals a platform for stimulating Atg8-PE conjugation Embo Rep., 14:206-211, 2013 Cited by PubMed: 23238393DOI: 10.1038/embor.2012.208 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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