3VWS
Dengue serotype 3 RNA-dependent RNA polymerase bound to NITD-107
Summary for 3VWS
Entry DOI | 10.2210/pdb3vws/pdb |
Descriptor | Non-structural protein 5, ZINC ION, 5-{[(4-chlorophenyl)sulfonyl]amino}-2-methyl-1-benzofuran-3-carboxylic acid, ... (5 entities in total) |
Functional Keywords | rna-dependent rna polymerase, rna polymerase, viral protein, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Dengue virus 3 |
Cellular location | Envelope protein E: Virion membrane; Multi- pass membrane protein: Q6DLV0 |
Total number of polymer chains | 1 |
Total formula weight | 74593.38 |
Authors | Noble, C.G.,Lescar, J. (deposition date: 2012-08-31, release date: 2013-02-27, Last modification date: 2023-11-08) |
Primary citation | Noble, C.G.,Lim, S.P.,Chen, Y.L.,Liew, C.W.,Yap, L.,Lescar, J.,Shi, P.-Y. Conformational flexibility of the Dengue virus RNA-dependent RNA polymerase revealed by a complex with an inhibitor J.Virol., 87:5291-5295, 2013 Cited by PubMed: 23408636DOI: 10.1128/JVI.00045-13 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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