3VTK
THYMIDINE KINASE FROM HERPES SIMPLEX VIRUS TYPE 1 IN COMPLEX WITH ADP AND 5-IODO-DEOXYURIDINE-MONOPHOSPHATE
Summary for 3VTK
Entry DOI | 10.2210/pdb3vtk/pdb |
Descriptor | THYMIDINE KINASE, ADENOSINE-5'-DIPHOSPHATE, 5-IODO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, ... (4 entities in total) |
Functional Keywords | key enzyme in thymidine salvage pathway, additional thymidylate kinase activity, target for anti-herpes viral drugs, transferase |
Biological source | Herpes simplex virus (type 1 / strain F) |
Total number of polymer chains | 1 |
Total formula weight | 38066.88 |
Authors | Wild, K.,Schulz, G.E. (deposition date: 1997-04-01, release date: 1997-10-22, Last modification date: 2024-02-28) |
Primary citation | Wild, K.,Bohner, T.,Folkers, G.,Schulz, G.E. The structures of thymidine kinase from herpes simplex virus type 1 in complex with substrates and a substrate analogue. Protein Sci., 6:2097-2106, 1997 Cited by PubMed: 9336833PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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