3VRI

HLA-B*57:01-RVAQLENVYI in complex with abacavir

Summary for 3VRI

• Entry DOI: 10.2210/pdb3vri/pdb
• Related: 3VRJ
• Descriptor: HLA class I histocompatibility antigen, B-57 alpha chain, Beta-2-microglobulin, 10-mer peptide, ... (6 entities in total)
• Functional Keywords: human leukocyte antigen, antigen presentation, immune system, t-cell receptor
• Biological source: Homo sapiens (human); More
• Cellular location: Membrane; Single-pass type I membrane protein: P18465; Secreted: P61769
• Total number of polymer chains: 3
• Total formula weight: 45217.33

Authors

Vivian, J.P.,Illing, P.T.,McCluskey, J.,Rossjohn, J. (deposition date: 2012-04-11, release date: 2012-05-30, Last modification date: 2023-11-08)

• Primary citation: Illing, P.T.,Vivian, J.P.,Dudek, N.L.,Kostenko, L.,Chen, Z.,Bharadwaj, M.,Miles, J.J.,Kjer-Nielsen, L.,Gras, S.,Williamson, N.A.,Burrows, S.R.,Purcell, A.W.,Rossjohn, J.,McCluskey, J.; Immune self-reactivity triggered by drug-modified HLA-peptide repertoire; Nature, 486:554-558, 2012; PubMed: 22722860; DOI: 10.1038/nature11147

Experimental method

X-RAY DIFFRACTION (1.6 Å)