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3VPP

Crystal Structure of the Human CLEC9A C-type Lectin-Like Domain

Summary for 3VPP
Entry DOI10.2210/pdb3vpp/pdb
DescriptorC-type lectin domain family 9 member A, CALCIUM ION (3 entities in total)
Functional Keywordsdendritic cell, c-type lectin-like domain, membrane, immune system
Biological sourceHomo sapiens (human)
Cellular locationMembrane; Single-pass type II membrane protein: Q6UXN8
Total number of polymer chains2
Total formula weight30199.51
Authors
Czabotar, P.E.,Zhang, J.G.,Policheni, A.N.,Shortman, K.,Lahoud, M.H.,Colman, P.M. (deposition date: 2012-03-07, release date: 2012-04-25, Last modification date: 2023-11-08)
Primary citationZhang, J.G.,Czabotar, P.E.,Policheni, A.N.,Caminschi, I.,Wan, S.S.,Kitsoulis, S.,Tullett, K.M.,Robin, A.Y.,Brammananth, R.,van Delft, M.F.,Lu, J.,O'Reilly, L.A.,Josefsson, E.C.,Kile, B.T.,Chin, W.J.,Mintern, J.D.,Olshina, M.A.,Wong, W.,Baum, J.,Wright, M.D.,Huang, D.C.,Mohandas, N.,Coppel, R.L.,Colman, P.M.,Nicola, N.A.,Shortman, K.,Lahoud, M.H.
The dendritic cell receptor Clec9A binds damaged cells via exposed actin filaments.
Immunity, 36:646-657, 2012
Cited by
PubMed: 22483802
DOI: 10.1016/j.immuni.2012.03.009
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.642 Å)
Structure validation

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