3VN9
Rifined Crystal structure of non-phosphorylated MAP2K6 in a putative auto-inhibition state
Replaces: 3AN0Summary for 3VN9
Entry DOI | 10.2210/pdb3vn9/pdb |
Descriptor | Dual specificity mitogen-activated protein kinase kinase 6, 9-{5-O-[(R)-hydroxy{[(S)-hydroxy(phosphonoamino)phosphoryl]oxy}phosphoryl]-beta-L-ribofuranosyl}-9H-purin-6-amine, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | auto-inhibition state, activation helices, mitogen-activated protein kinase kinase, amp-pnp binding, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus : P52564 |
Total number of polymer chains | 1 |
Total formula weight | 38899.70 |
Authors | Kinoshita, T.,Matsuzaka, H.,Nakai, R.,Kirii, Y.,Yokota, K.,Tada, T.,Matsumoto, T. (deposition date: 2012-01-05, release date: 2012-02-29, Last modification date: 2023-11-08) |
Primary citation | Matsumoto, T.,Kinoshita, T.,Matsuzaka, H.,Nakai, R.,Kirii, Y.,Yokota, K.,Tada, T. Crystal structure of non-phosphorylated MAP2K6 in a putative auto-inhibition state J.Biochem., 151:541-549, 2012 Cited by PubMed: 22383536DOI: 10.1093/jb/mvs023 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
Download full validation report