3V6B
VEGFR-2/VEGF-E complex structure
Summary for 3V6B
Entry DOI | 10.2210/pdb3v6b/pdb |
Related | 2GNN 2X1W 2X1X 3V2A |
Descriptor | VEGF-E, Vascular endothelial growth factor receptor 2 (2 entities in total) |
Functional Keywords | ig-homology domain, vegfr-2, growth factor receptor, vegf ligand, angiogenesis, membrane, vegf-e, orf virus, hormone-signaling protein complex, hormone/signaling protein |
Biological source | Orf virus (ORFV) More |
Cellular location | Cell junction . Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted . Isoform 3: Secreted: P35968 |
Total number of polymer chains | 2 |
Total formula weight | 63198.73 |
Authors | Brozzo, M.S.,Leppanen, V.-M.,Winkler, F.K.,Kisko, K.,Ballmer-Hofer, K. (deposition date: 2011-12-19, release date: 2012-01-18, Last modification date: 2024-04-03) |
Primary citation | Brozzo, M.S.,Bjelic, S.,Kisko, K.,Schleier, T.,Leppanen, V.M.,Alitalo, K.,Winkler, F.K.,Ballmer-Hofer, K. Thermodynamic and structural description of allosterically regulated VEGFR-2 dimerization. Blood, 119:1781-1788, 2012 Cited by PubMed: 22207738DOI: 10.1182/blood-2011-11-390922 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.205 Å) |
Structure validation
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