3V0Q
Crystal structure of the Fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with UDP and H-antigen acceptor
Summary for 3V0Q
Entry DOI | 10.2210/pdb3v0q/pdb |
Related | 3IOH 3IOI 3IOJ |
Descriptor | Histo-blood group ABO system transferase, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE, ... (7 entities in total) |
Functional Keywords | gta, abo, cisab mutant, rossmann fold, "closed" conformation, glycosyltransferase, glycoprotein, blood group antigen, udp-galnac, metal-binding, manganese, glycosylation, transmembrane, golgi apparatus, secreted, signal-anchor, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein: P16442 |
Total number of polymer chains | 2 |
Total formula weight | 71571.64 |
Authors | Palcic, M.M.,Jorgensen, R. (deposition date: 2011-12-08, release date: 2013-01-23, Last modification date: 2023-09-13) |
Primary citation | Jrgensen, R.,Pesnot, T.,Lee, H.J.,Palcic, M.M.,Wagner, G.K. Base-modified Donor Analogues Reveal Novel Dynamic Features of a Glycosyltransferase. J.Biol.Chem., 288:26201-26208, 2013 Cited by PubMed: 23836908DOI: 10.1074/jbc.M113.465963 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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