3UYR

Structure of a monoclonal antibody complexed with its MHC-I antigen

Summary for 3UYR

• Entry DOI: 10.2210/pdb3uyr/pdb
• Related: 3UO1 3V4U 3V52
• Descriptor: antibody Fab heavy chain, antibody Fab light chain, H-2 class I histocompatibility antigen, L-D alpha chain, ... (5 entities in total)
• Functional Keywords: ig-fold 3, 10 helix, immune system
• Biological source: Mus musculus (mouse); More
• Cellular location: Membrane; Single-pass type I membrane protein: P01897
• Total number of polymer chains: 3
• Total formula weight: 48180.65

Authors

Margulies, D.H.,Mage, M.G.,Wang, R.,Natarajan, K. (deposition date: 2011-12-06, release date: 2012-07-25, Last modification date: 2012-08-01)

• Primary citation: Mage, M.G.,Dolan, M.A.,Wang, R.,Boyd, L.F.,Revilleza, M.J.,Robinson, H.,Natarajan, K.,Myers, N.B.,Hansen, T.H.,Margulies, D.H.; The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics.; J.Immunol., 189:1391-1399, 2012; PubMed: 22753930; DOI: 10.4049/jimmunol.1200831

Experimental method

X-RAY DIFFRACTION (1.7 Å)