3UTS
1E6-A*0201-ALWGPDPAAA Complex, Monoclinic
Summary for 3UTS
Entry DOI | 10.2210/pdb3uts/pdb |
Related | 3UTP 3UTQ 3UTT |
Descriptor | HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Insulin, ... (8 entities in total) |
Functional Keywords | major histocompatibility complex, human leukocyte antigen, type i diabetes, t cell receptor, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P01892 Secreted: P61769 P01308 |
Total number of polymer chains | 10 |
Total formula weight | 191256.75 |
Authors | Rizkallah, P.J.,Cole, D.K.,Sewell, A.K.,Bulek, A.M. (deposition date: 2011-11-26, release date: 2012-01-25, Last modification date: 2012-03-07) |
Primary citation | Bulek, A.M.,Cole, D.K.,Skowera, A.,Dolton, G.,Gras, S.,Madura, F.,Fuller, A.,Miles, J.J.,Gostick, E.,Price, D.A.,Drijfhout, J.W.,Knight, R.R.,Huang, G.C.,Lissin, N.,Molloy, P.E.,Wooldridge, L.,Jakobsen, B.K.,Rossjohn, J.,Peakman, M.,Rizkallah, P.J.,Sewell, A.K. Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes. Nat.Immunol., 13:283-289, 2012 Cited by PubMed: 22245737DOI: 10.1038/ni.2206 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.712 Å) |
Structure validation
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