3UON
Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist
Summary for 3UON
Entry DOI | 10.2210/pdb3uon/pdb |
Descriptor | Human M2 muscarinic acetylcholine, receptor T4 lysozyme fusion protein, (3R)-1-azabicyclo[2.2.2]oct-3-yl hydroxy(diphenyl)acetate, beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | g protein-coupled receptor, gpcr, acetylcholine receptor, signaling protein-antagonist complex, signaling protein/antagonist |
Biological source | Homo sapiens More |
Total number of polymer chains | 1 |
Total formula weight | 53283.02 |
Authors | Haga, K.,Kruse, A.C.,Asada, H.,Yurugi-Kobayashi, T.,Shiroishi, M.,Zhang, C.,Weis, W.I.,Okada, T.,Kobilka, B.K.,Haga, T.,Kobayashi, T. (deposition date: 2011-11-16, release date: 2012-02-01, Last modification date: 2023-09-13) |
Primary citation | Haga, K.,Kruse, A.C.,Asada, H.,Yurugi-Kobayashi, T.,Shiroishi, M.,Zhang, C.,Weis, W.I.,Okada, T.,Kobilka, B.K.,Haga, T.,Kobayashi, T. Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist. Nature, 482:547-551, 2012 Cited by PubMed: 22278061DOI: 10.1038/nature10753 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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