3UFA
Crystal structure of the staphylococcal serine protease SplA in complex with a specific phosphonate inhibitor
Summary for 3UFA
Entry DOI | 10.2210/pdb3ufa/pdb |
Related PRD ID | PRD_000908 |
Descriptor | Serine protease splA, N-(3-carboxypropanoyl)-L-valyl-N-[(1S)-2-phenyl-1-phosphonoethyl]-L-prolinamide, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | chymotrypsin like fold, serine protease, extracellular protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Staphylococcus aureus |
Cellular location | Secreted: Q2FXC2 |
Total number of polymer chains | 2 |
Total formula weight | 44872.28 |
Authors | Zdzalik, M.,Pietrusewicz, E.,Pustelny, K.,Stec-Niemczyk, J.,Popowicz, G.M.,Potempa, J.,Oleksyszyn, J.,Dubin, G. (deposition date: 2011-10-31, release date: 2013-01-23, Last modification date: 2014-03-05) |
Primary citation | Burchacka, E.,Zdzalik, M.,Niemczyk, J.S.,Pustelny, K.,Popowicz, G.,Wladyka, B.,Dubin, A.,Potempa, J.,Sienczyk, M.,Dubin, G.,Oleksyszyn, J. Development and binding characteristics of phosphonate inhibitors of SplA protease from Staphylococcus aureus. Protein Sci., 23:179-189, 2014 Cited by PubMed: 24375505DOI: 10.1002/pro.2403 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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