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3U7X

Crystal structure of the human eIF4E-4EBP1 peptide complex without cap

Replaces:  3SMU
Summary for 3U7X
Entry DOI10.2210/pdb3u7x/pdb
DescriptorEukaryotic translation initiation factor 4E, Eukaryotic translation initiation factor 4E-binding protein 1, SULFATE ION, ... (5 entities in total)
Functional Keywordseif4e, 4ebp1, mrna export, structural genomics consortium, sgc, translation
Biological sourceHomo sapiens (human)
More
Cellular locationCytoplasm, P-body : P06730
Total number of polymer chains4
Total formula weight55360.25
Authors
Primary citationSiddiqui, N.,Tempel, W.,Nedyalkova, L.,Volpon, L.,Wernimont, A.K.,Osborne, M.J.,Park, H.W.,Borden, K.L.
Structural Insights into the Allosteric Effects of 4EBP1 on the Eukaryotic Translation Initiation Factor eIF4E.
J.Mol.Biol., 415:781-792, 2012
Cited by
PubMed: 22178476
DOI: 10.1016/j.jmb.2011.12.002
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation

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