3U2B

Structure of the Sox4 HMG domain bound to DNA

Summary for 3U2B

• Entry DOI: 10.2210/pdb3u2b/pdb
• Related: 1gt0 3f27
• Descriptor: DNA (5'-D(*GP*TP*CP*TP*CP*TP*AP*TP*TP*GP*TP*CP*CP*TP*GP*G)-3'), DNA (5'-D(*CP*CP*AP*GP*GP*AP*CP*AP*AP*TP*AP*GP*AP*GP*AP*C)-3'), Transcription factor SOX-4, ... (4 entities in total)
• Functional Keywords: hmg domain, transcriptional regulation, transcription-dna complex, transcription/dna
• Biological source: Mus musculus (mouse); More
• Cellular location: Nucleus: Q06831
• Total number of polymer chains: 3
• Total formula weight: 19514.90

Authors

Jauch, R.,Ng, C.K.L.,Kolatkar, P.R. (deposition date: 2011-10-03, release date: 2011-12-28, Last modification date: 2024-03-20)

• Primary citation: Jauch, R.,Ng, C.K.L.,Narasimhan, K.,Kolatkar, P.R.; The crystal structure of the Sox4 HMG domain-DNA complex suggests a mechanism for positional interdependence in DNA recognition; Biochem.J., 443:39-47, 2012; PubMed: 22181698; DOI: 10.1042/BJ20111768

Experimental method

X-RAY DIFFRACTION (2.402 Å)