3TUV

Crystal structure of insulysin with bound ATP

Summary for 3TUV

• Entry DOI: 10.2210/pdb3tuv/pdb
• Descriptor: Insulin-degrading enzyme, Peptide, ADENOSINE-5'-TRIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: thermolysin-like fold active site region, hydrolyase, peptidase, hydrolase
• Biological source: Rattus norvegicus (brown rat,rat,rats); More
• Cellular location: Cytoplasm: P35559
• Total number of polymer chains: 2
• Total formula weight: 118645.33

Authors

Rodgers, D.W.,Noinaj, N. (deposition date: 2011-09-19, release date: 2011-10-26, Last modification date: 2024-02-28)

• Primary citation: Noinaj, N.,Song, E.S.,Bhasin, S.,Alper, B.J.,Schmidt, W.K.,Hersh, L.B.,Rodgers, D.W.; Anion Activation Site of Insulin-degrading Enzyme.; J.Biol.Chem., 287:48-57, 2012; PubMed: 22049080; DOI: 10.1074/jbc.M111.264614

Experimental method

X-RAY DIFFRACTION (2.27 Å)