3TUG
Crystal structure of the HECT domain of ITCH E3 ubiquitin ligase
Summary for 3TUG
Entry DOI | 10.2210/pdb3tug/pdb |
Descriptor | E3 ubiquitin-protein ligase Itchy homolog, CHLORIDE ION, UNKNOWN ATOM OR ION, ... (4 entities in total) |
Functional Keywords | structural genomics, structural genomics consortium, sgc, catalytic domain, e3 ligase, ligase |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane: Q96J02 |
Total number of polymer chains | 1 |
Total formula weight | 47525.59 |
Authors | Dong, A.,Dobrovetsky, E.,Xue, S.,Butler, C.,Wernimont, A.,Walker, J.R.,Tempel, W.,Dhe-Paganon, S.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Tong, Y.,Structural Genomics Consortium (SGC) (deposition date: 2011-09-16, release date: 2011-10-12, Last modification date: 2023-09-13) |
Primary citation | Dobrovetsky, E.,Dong, A.,Xue, S.,Butler, C.,Wernimont, A.,Walker, J.R.,Tempel, W.,Dhe-Paganon, S.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Tong, Y. Crystal structure of the HECT domain of ITCH E3 ubiquitin ligase To be Published, |
Experimental method | X-RAY DIFFRACTION (2.27 Å) |
Structure validation
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