3TF2
Crystal structure of the cap free human translation initiation factor eIF4E
Summary for 3TF2
Entry DOI | 10.2210/pdb3tf2/pdb |
Descriptor | Eukaryotic translation initiation factor 4E, UNKNOWN ATOM OR ION (3 entities in total) |
Functional Keywords | eif4e, translation, mrna export, structural genomics, structural genomics consortium, sgc |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, P-body : P06730 |
Total number of polymer chains | 4 |
Total formula weight | 100520.97 |
Authors | Siddiqui, N.,Tempel, W.,Nedyalkova, L.,Wernimont, A.K.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Borden, K.L.B.,Park, H.,Structural Genomics Consortium (SGC) (deposition date: 2011-08-15, release date: 2011-08-31, Last modification date: 2023-09-13) |
Primary citation | Siddiqui, N.,Tempel, W.,Nedyalkova, L.,Volpon, L.,Wernimont, A.K.,Osborne, M.J.,Park, H.W.,Borden, K.L. Structural insights into the allosteric effects of 4EBP1 on the eukaryotic translation initiation factor eIF4E. J.Mol.Biol., 415:781-792, 2012 Cited by PubMed: 22178476DOI: 10.1016/j.jmb.2011.12.002 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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