3SRG

Serum paraoxonase-1 by directed evolution at pH 6.5 in complex with 2-hydroxyquinoline

Summary for 3SRG

Entry DOI	10.2210/pdb3srg/pdb
Related	1V04 3SRE
Descriptor	serum paraoxonase, CALCIUM ION, QUINOLIN-2(1H)-ONE, ... (7 entities in total)
Functional Keywords	directed evolution, 6-blades-propeller fold, hydrolase
Biological source	artificial gene
Total number of polymer chains	1
Total formula weight	40530.77
Authors	Ben David, M.,Elias, M.,Silman, I.,Sussman, J.L.,Tawfik, D.S. (deposition date: 2011-07-07, release date: 2012-03-21, Last modification date: 2023-09-13)
Primary citation	Ben-David, M.,Elias, M.,Filippi, J.J.,Dunach, E.,Silman, I.,Sussman, J.L.,Tawfik, D.S. Catalytic versatility and backups in enzyme active sites: the case of serum paraoxonase 1. J.Mol.Biol., 418:181-196, 2012 Cited by PubMed: 22387469 DOI: 10.1016/j.jmb.2012.02.042 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.19 Å)

Structure validation