3SQP
Structure of human glutathione reductase complexed with pyocyanin, an agent with antimalarial activity
Summary for 3SQP
Entry DOI | 10.2210/pdb3sqp/pdb |
Descriptor | Glutathione reductase, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ... (6 entities in total) |
Functional Keywords | cellular reductants, glutathione reductase, plasmodium falciparum, pyocyanin, alternative initiation, flavoprotein, mitochondrion, oxidoreductase, phosphoprotein, redox-active center, transit peptide, oxidoreductase-antibiotic complex, oxidoreductase/antibiotic |
Biological source | Homo sapiens |
Cellular location | Isoform Mitochondrial: Mitochondrion. Isoform Cytoplasmic: Cytoplasm: P00390 |
Total number of polymer chains | 2 |
Total formula weight | 105832.49 |
Authors | Fritz-Wolf, K.,Schirmer, R.H.,Koenig, I.,Goebel, U. (deposition date: 2011-07-06, release date: 2011-09-14, Last modification date: 2023-09-13) |
Primary citation | Kasozi, D.M.,Gromer, S.,Adler, H.,Zocher, K.,Rahlfs, S.,Wittlin, S.,Fritz-Wolf, K.,Schirmer, R.H.,Becker, K. The bacterial redox signaller pyocyanin as an antiplasmodial agent: comparisons with its thioanalog methylene blue. Redox Rep., 16:154-165, 2011 Cited by PubMed: 21888766DOI: 10.1179/174329211X13049558293678 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.21 Å) |
Structure validation
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