3SHT
Crystal structure of human MCPH1 tandem BRCT domains
Summary for 3SHT
Entry DOI | 10.2210/pdb3sht/pdb |
Related | 3SHV |
Descriptor | Microcephalin (2 entities in total) |
Functional Keywords | tandem brct domains, cell cycle |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome : Q8NEM0 |
Total number of polymer chains | 3 |
Total formula weight | 68617.85 |
Authors | Shao, Z.H.,Li, F.D.,Yan, W. (deposition date: 2011-06-17, release date: 2011-12-28, Last modification date: 2023-11-01) |
Primary citation | Shao, Z.H.,Li, F.D.,Sy, S.M.-H.,Yan, W.,Zhang, Z.,Gong, D.,Wen, B.,Huen, M.S.Y.,Gong, Q.,Wu, J.,Shi, Y. Specific recognition of phosphorylated tail of H2AX by the tandem BRCT domains of MCPH1 revealed by complex structure J.Struct.Biol., 177:459-468, 2012 Cited by PubMed: 22154951DOI: 10.1016/j.jsb.2011.11.022 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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