3SEJ

Structural characterization of a GII.4 2004 norovirus variant (TCH05) bound to Secretor Lewis HBGA (LeB)

Summary for 3SEJ

Entry DOI	10.2210/pdb3sej/pdb
Descriptor	Capsid, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose (3 entities in total)
Functional Keywords	protein-carbohydrate complex, leb bound, receptor binding, human blood group antigens, carbohydrate/sugar binding, lewis family, viral protein
Biological source	Norovirus Hu/GII.4/2004/NL
Total number of polymer chains	10
Total formula weight	351310.47
Authors	Shanker, S.,Choi, J.-M.,Sankaran, B.,Atmar, R.L.,Estes, M.K.,Prasad, B.V.V. (deposition date: 2011-06-10, release date: 2011-07-13, Last modification date: 2024-02-28)
Primary citation	Shanker, S.,Choi, J.M.,Sankaran, B.,Atmar, R.L.,Estes, M.K.,Prasad, B.V. Structural Analysis of Histo-Blood Group Antigen Binding Specificity in a Norovirus GII.4 Epidemic Variant: Implications for Epochal Evolution. J.Virol., 85:8635-8645, 2011 Cited by PubMed: 21715503 DOI: 10.1128/JVI.00848-11 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.041 Å)

Structure validation