3SC8
Crystal structure of an intramolecular human telomeric DNA G-quadruplex bound by the naphthalene diimide BMSG-SH-3
Summary for 3SC8
Entry DOI | 10.2210/pdb3sc8/pdb |
Descriptor | Human telomeric repeat sequence, POTASSIUM ION, 2,7-bis[3-(4-methylpiperazin-1-yl)propyl]-4,9-bis{[3-(4-methylpiperazin-1-yl)propyl]amino}benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetrone, ... (4 entities in total) |
Functional Keywords | g-quadruplex, intramolecular, ligand-complex, telomeric, dna |
Total number of polymer chains | 1 |
Total formula weight | 7957.93 |
Authors | Collie, G.W.,Promontorio, R.,Parkinson, G.N. (deposition date: 2011-06-07, release date: 2012-02-15, Last modification date: 2023-09-13) |
Primary citation | Collie, G.W.,Promontorio, R.,Hampel, S.M.,Micco, M.,Neidle, S.,Parkinson, G.N. Structural basis for telomeric g-quadruplex targeting by naphthalene diimide ligands. J.Am.Chem.Soc., 134:2723-2731, 2012 Cited by PubMed: 22280460DOI: 10.1021/ja2102423 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.302 Å) |
Structure validation
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