3RZE
Structure of the human histamine H1 receptor in complex with doxepin
Summary for 3RZE
Entry DOI | 10.2210/pdb3rze/pdb |
Descriptor | Histamine H1 receptor, Lysozyme chimera, (3E)-3-(dibenzo[b,e]oxepin-11(6H)-ylidene)-N,N-dimethylpropan-1-amine, (3Z)-3-(dibenzo[b,e]oxepin-11(6H)-ylidene)-N,N-dimethylpropan-1-amine, ... (6 entities in total) |
Functional Keywords | structural genomics, psi-biology, membrane protein, gpcr network, gpcr, hydrolase |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane ; Multi-pass membrane protein : P35367 |
Total number of polymer chains | 1 |
Total formula weight | 53582.80 |
Authors | Shimamura, T.,Han, G.W.,Shiroishi, M.,Weyand, S.,Tsujimoto, H.,Winter, G.,Katritch, V.,Abagyan, R.,Cherezov, V.,Liu, W.,Kobayashi, T.,Stevens, R.,Iwata, S.,GPCR Network (GPCR) (deposition date: 2011-05-11, release date: 2011-06-15, Last modification date: 2023-09-13) |
Primary citation | Shimamura, T.,Shiroishi, M.,Weyand, S.,Tsujimoto, H.,Winter, G.,Katritch, V.,Abagyan, R.,Cherezov, V.,Liu, W.,Han, G.W.,Kobayashi, T.,Stevens, R.C.,Iwata, S. Structure of the human histamine H1 receptor complex with doxepin. Nature, 475:65-70, 2011 Cited by PubMed: 21697825DOI: 10.1038/nature10236 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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