3R6G
Crystal structure of active caspase-2 bound with Ac-VDVAD-CHO
Summary for 3R6G
Entry DOI | 10.2210/pdb3r6g/pdb |
Related | 3R5J 3R6L 3R7B 3R7N 3R7S |
Related PRD ID | PRD_001048 |
Descriptor | Caspase-2 subunit p18, Caspase-2 subunit p12, Peptide Inhibitor (ACE)VDVAD-CHO, ... (4 entities in total) |
Functional Keywords | hydrolase, apoptosis, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 63084.18 |
Authors | |
Primary citation | Tang, Y.,Wells, J.A.,Arkin, M.R. Structural and enzymatic insights into caspase-2 protein substrate recognition and catalysis. J.Biol.Chem., 286:34147-34154, 2011 Cited by PubMed: 21828056DOI: 10.1074/jbc.M111.247627 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.07 Å) |
Structure validation
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