3R69

Molecular analysis of the interaction of the HDL-receptor SR-BI with the PDZ3 domain of its adaptor protein PDZK1

Summary for 3R69

Entry DOI	10.2210/pdb3r69/pdb
Related	2D90 3R68
Descriptor	Na(+)/H(+) exchange regulatory cofactor NHE-RF3, Scavenger receptor class B member 1, CITRIC ACID (3 entities in total)
Functional Keywords	pdz domain, adaptor protein, sr-bi, chimera, signaling protein
Biological source	Mus musculus (mouse,mouse) More
Cellular location	Cell membrane ; Multi-pass membrane protein . Isoform 1: Cell membrane . Isoform 2: Cell membrane : Q61009
Total number of polymer chains	2
Total formula weight	19017.55
Authors	Kocher, O.,Birrane, G.,Krieger, M. (deposition date: 2011-03-21, release date: 2011-05-18, Last modification date: 2023-09-13)
Primary citation	Kocher, O.,Birrane, G.,Yesilaltay, A.,Shechter, S.,Pal, R.,Daniels, K.,Krieger, M. Identification of the PDZ3 Domain of the Adaptor Protein PDZK1 as a Second, Physiologically Functional Binding Site for the C Terminus of the High Density Lipoprotein Receptor Scavenger Receptor Class B Type I. J.Biol.Chem., 286:25171-25186, 2011 Cited by PubMed: 21602281 DOI: 10.1074/jbc.M111.242362 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.499 Å)

Structure validation