3R58
AKR1C3 complex with naproxen
Summary for 3R58
Entry DOI | 10.2210/pdb3r58/pdb |
Related | 3R43 3R6I |
Descriptor | Aldo-keto reductase family 1 member C3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, (2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid, ... (5 entities in total) |
Functional Keywords | tim barrel, aldo-keto reductase, nitro reductase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P42330 |
Total number of polymer chains | 1 |
Total formula weight | 39199.31 |
Authors | Yosaatmadja, Y.,Teague, R.M.,Flanagan, J.U.,Squire, C.J. (deposition date: 2011-03-18, release date: 2012-03-28, Last modification date: 2024-02-21) |
Primary citation | Flanagan, J.U.,Yosaatmadja, Y.,Teague, R.M.,Chai, M.Z.,Turnbull, A.P.,Squire, C.J. Crystal structures of three classes of non-steroidal anti-inflammatory drugs in complex with aldo-keto reductase 1C3. Plos One, 7:e43965-e43965, 2012 Cited by PubMed: 22937138DOI: 10.1371/journal.pone.0043965 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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