3QYW
Crystal structure of ERK2 in complex with an inhibitor
Summary for 3QYW
Entry DOI | 10.2210/pdb3qyw/pdb |
Related | 3QYU 3QYZ |
Descriptor | Mitogen-activated protein kinase 1, 6-(3-bromophenyl)-7H-purin-2-amine, DIMETHYL SULFOXIDE, ... (5 entities in total) |
Functional Keywords | transferase, serine/threonine-protein kinase, atp-binding cell cycle, phosphorylation, protein kinase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Rattus norvegicus (brown rat,rat,rats) |
Cellular location | Cytoplasm, cytoskeleton, spindle : P63086 |
Total number of polymer chains | 1 |
Total formula weight | 43403.06 |
Authors | Gelin, M.,Pochet, S.,Hoh, F.,Pirochi, M.,Guichou, J.-F.,Ferrer, J.-L.,Labesse, G. (deposition date: 2011-03-04, release date: 2011-08-24, Last modification date: 2017-11-08) |
Primary citation | le Maire, A.,Gelin, M.,Pochet, S.,Hoh, F.,Pirocchi, M.,Guichou, J.F.,Ferrer, J.L.,Labesse, G. In-plate protein crystallization, in situ ligand soaking and X-ray diffraction. Acta Crystallogr.,Sect.D, 67:747-755, 2011 Cited by PubMed: 21904027DOI: 10.1107/S0907444911023249 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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