3QWR
Crystal structure of IL-23 in complex with an adnectin
Summary for 3QWR
Entry DOI | 10.2210/pdb3qwr/pdb |
Related | 3QWQ |
Descriptor | Interleukin-12 subunit beta, Interleukin-23 subunit alpha, ADNECTIN, ... (5 entities in total) |
Functional Keywords | four-helix bundle cytokine, ig domain, glycoprotein, immunoglobulin domain, secreted, antiviral defense, immune response, inflammatory response, innate immunity, tissue remodeling, adnectin, engineered binding protein, antibody mimic, protein binding-cytokine complex, protein binding/cytokine |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 66664.54 |
Authors | Wei, A.,Sheriff, S. (deposition date: 2011-02-28, release date: 2012-02-01, Last modification date: 2023-09-13) |
Primary citation | Ramamurthy, V.,Krystek, S.R.,Bush, A.,Wei, A.,Emanuel, S.L.,Das Gupta, R.,Janjua, A.,Cheng, L.,Murdock, M.,Abramczyk, B.,Cohen, D.,Lin, Z.,Morin, P.,Davis, J.H.,Dabritz, M.,McLaughlin, D.C.,Russo, K.A.,Chao, G.,Wright, M.C.,Jenny, V.A.,Engle, L.J.,Furfine, E.,Sheriff, S. Structures of adnectin/protein complexes reveal an expanded binding footprint. Structure, 20:259-269, 2012 Cited by PubMed: 22325775DOI: 10.1016/j.str.2011.11.016 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.25 Å) |
Structure validation
Download full validation report