3QTC

Crystal structure of the catalytic domain of MmOmeRS, an O-methyl tyrosyl-tRNA synthetase evolved from Methanosarcina mazei PylRS, complexed with O-methyl tyrosine and AMP-PNP

Summary for 3QTC

Entry DOI	10.2210/pdb3qtc/pdb
Descriptor	Pyrrolysyl-tRNA synthetase, MAGNESIUM ION, O-methyl-L-tyrosine, ... (6 entities in total)
Functional Keywords	pyrrolysyl-trna synthetase, aminoacyl-trna synthetase, atp binding, o-methyl tyrosine binding, magnesium binding, aminoacylation, esterification, ligase
Biological source	Methanosarcina mazei (Methanosarcina frisia)
Cellular location	Cytoplasm (By similarity): Q8PWY1
Total number of polymer chains	1
Total formula weight	34555.75
Authors	Dellas, N.,Takimoto, J.K.,Noel, J.P.,Wang, L. (deposition date: 2011-02-22, release date: 2011-05-25, Last modification date: 2023-12-06)
Primary citation	Takimoto, J.K.,Dellas, N.,Noel, J.P.,Wang, L. Stereochemical Basis for Engineered Pyrrolysyl-tRNA Synthetase and the Efficient in Vivo Incorporation of Structurally Divergent Non-native Amino Acids. Acs Chem.Biol., 6:733-743, 2011 Cited by PubMed: 21545173 DOI: 10.1021/cb200057a PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation